ONCC AOCNP Certification Exam Syllabus
Welcome to the official MedicoExam syllabus guide for the ONCC Advanced Oncology Certified Nurse Practitioner certification. This page delivers a clear, structured overview of the ONCC AOCNP exam, including key exam details, syllabus topics, and preparation references to support effective study planning. The ONCC Advanced Oncology Certified Nurse Practitioner (AOCNP) is intended for professionals pursuing roles aligned with Advanced Practice Nursing Certification, with assessment centered on applied competencies such as Cancer assessment and individualized treatment planning, oncology treatment and supportive care management, oncologic emergency and evidence-based advanced practice management within real-world settings like Adult oncology clinical practice, nursing administration and education, oncology research and consultation settings.
The syllabus outline below reflects the core domains and expectations defined by the official ONCC certification framework and aligns with the cognitive and professional standards assessed in the ONCC AOCNP exam. Candidates can use this guide alongside official vendor resources and structured practice to align their preparation with current exam standards and professional expectations for Adult oncology nurse practitioners, oncology advanced practice registered nurses, nurse practitioners practicing in adult oncology and related roles
ONCC AOCNP Exam Summary and Key Details
| Exam Name | ONCC Advanced Oncology Certified Nurse Practitioner |
| Credential | ONCC Advanced Oncology Certified Nurse Practitioner (AOCNP) |
| Vendor | Oncology Nursing Certification Corporation (ONCC) |
| Exam Code | AOCNP » ONCC AOCNP Certification Practice Exam |
| Exam Delivery Mode | Computer-based testing at PSI test centers |
| Exam Duration | 180 mins |
| Number of Questions | 165 (125 scored and 40 unscored) |
| Passing Score | 55 on a scale of 25-75 |
| Exam Price |
ONS/APHON Member - $300 Nonmember - $420 |
| Scheduling Window | 90-day ATT testing window; testing is available year-round in the United States, its territories, and Canada; 2026 international testing is offered June 1–30, 2026 |
| Schedule Exam | ONCC |
| Trainings/Resources | 2026 AOCNP® Test References |
| Sample Questions | ONCC AOCNP Exam Sample Questions |
| Recommended Practice | ONCC AOCNP Certification Practice Exam |
ONCC AOCNP Exam Syllabus Topics and Weighting
| Topic Areas | Topic Details, Courses, Books | Weighting |
|---|---|---|
| Cancer Continuum |
- Screening and Prevention
- Assessment and Diagnosis
- Plan of care across the cancer continuum
|
28% |
| Cancer Treatment and Supportive Care |
- Clinical trials and research studies - Systemic therapy (e.g., chemotherapy, hormonal, targeted, immunotherapy, cellular therapy) - Localized therapy (e.g., intravascular, intraperitoneal, intrathecal, intra-arterial) - Surgical interventions - Radiation therapy - Blood and marrow transplantation - Multimodal therapy - Complementary, alternative, and integrative therapies - Etiology, incidence, and patterns for treatment-related symptoms (e.g., acute, late, long term) - Response to therapy (e.g., imaging, biomarkers, clinical response) - Palliative care - Pharmacologic interventions for symptom management - Nonpharmacologic interventions for symptom management - Interrelationship between disease, treatment, and comorbid conditions - Controlled substance safety |
45% |
| Oncologic Emergencies |
- Etiology, risk factors, and prevention strategies - Assessment strategies (e.g., physical examination, differential diagnosis) - Interventions for treatment |
12% |
| Psychosocial Issues |
- Psychosocial assessment instruments, tools, and questionnaires - Risk factors and at-risk populations (e.g., disparities in culture, socioeconomic status, age, LGBTQIA, gender identity, occupations, medical history, geographic location) - Psychosocial and emotional sequelae of disease and treatment (e.g., coping, fear of recurrence, depression, post-traumatic stress disorder, family interpersonal relationships) - Psychiatric and psychosocial comorbidities (e.g., anxiety, depression, cognitive impairment) - Community resources |
10% |
| Professional Practice and Roles of the APRN |
- Cultural competence and implicit bias - Legal and regulatory requirements (e.g., licensing, documentation) - Accreditation standards (e.g., Commission on Cancer, National Cancer Institute, FACT) - Ethical/legal issues - Advanced practice standards of care - Outcomes of APRN interventions and evidence-based care on individuals, groups, and systems - Quality improvement strategies - Competency evaluation of self and others (e.g., new hires, peer review) - Peer education and support (e.g., needs assessment, preparation of materials, mentorship) |
5% |
The ONCC AOCNP certification exam is designed to assess both theoretical knowledge and applied professional judgment in Advanced Practice Nursing Certification. The exam evaluates competencies such as Cancer assessment and individualized treatment planning, oncology treatment and supportive care management, oncologic emergency and evidence-based advanced practice management, ensuring candidates are prepared for real-world responsibilities as Adult oncology nurse practitioners, oncology advanced practice registered nurses, nurse practitioners practicing in adult oncology and related roles working in settings such as Adult oncology clinical practice, nursing administration and education, oncology research and consultation settings.
To prepare effectively for the ONCC Advanced Oncology Certified Nurse Practitioner exam, candidates are encouraged to review official vendor materials, complete structured practice assessments, and gain hands-on experience relevant to their professional role.
