ACRP Principal Investigator Syllabus

Welcome to the official MedicoExam syllabus guide for the ACRP Certified Principal Investigator certification. This page delivers a clear, structured overview of the ACRP CPI exam, including key exam details, syllabus topics, and preparation references to support effective study planning. The ACRP Certified Principal Investigator (CPI) is intended for professionals pursuing roles aligned with Flagship Certification, with assessment centered on applied competencies such as participant safety and ethical oversight, protocol implementation and trial conduct, site operations and data integrity within real-world settings like clinical trial sites, academic medical centers, research hospitals and institutions.

The syllabus outline below reflects the core domains and expectations defined by the official ACRP certification framework and aligns with the cognitive and professional standards assessed in the ACRP CPI exam. Candidates can use this guide alongside official vendor resources and structured practice to align their preparation with current exam standards and professional expectations for principal investigators, sub-investigators, clinical investigators and related roles