ACRP Principal Investigator Syllabus

Explore 2 resources related to ACRP Principal Investigator Syllabus on MedicoExam. These resources help certification candidates understand key aspects of exam preparation, including exam structure, study strategies, and expectations for scenario-based or applied assessments. Reviewing these materials can help improve readiness and confidence before attempting the certification exam.

ACRP CPI Practice Test and Exam Guide: Six Weighted Areas

The ACRP Certified Principal Investigator (CPI) exam has 125 questions (100 scored and 25 pretest), runs for 180 minutes and reports a scaled score, with 600 on a 200-800 scale needed to pass. It tests six areas of clinical research, led by ethical and safety considerations at 22% of the weighting.

The exam is built for people who have already led or co-led studies, so preparation is mostly about judgment, not memory. To see where you stand before you pay ACRP, take the CPI practice test first and use that result as your starting point.

Clinical research investigator at a desk with a laptop and protocol binder preparing for the CPI exam

ACRP CPI Certification Exam Syllabus

ACRP CPI syllabus for ACRP Certified Principal Investigator (CPI) preparation

Welcome to the official MedicoExam syllabus guide for the ACRP Certified Principal Investigator certification. This page delivers a clear, structured overview of the ACRP CPI exam, including key exam details, syllabus topics, and preparation references to support effective study planning. The ACRP Certified Principal Investigator (CPI) is intended for professionals pursuing roles aligned with Flagship Certification, with assessment centered on applied competencies such as participant safety and ethical oversight, protocol implementation and trial conduct, site operations and data integrity within real-world settings like clinical trial sites, academic medical centers, research hospitals and institutions.

The syllabus outline below reflects the core domains and expectations defined by the official ACRP certification framework and aligns with the cognitive and professional standards assessed in the ACRP CPI exam. Candidates can use this guide alongside official vendor resources and structured practice to align their preparation with current exam standards and professional expectations for principal investigators, sub-investigators, clinical investigators and related roles

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